What It’s Like to Smoke Salvia for Science
I was the final volunteer in the world's first brain imaging study on salvia divinorum.
Scientists Identify Key Neural Mechanisms Behind an LSD Trip
LSD appears to cause information to disintegrate as it is passed through a neural circuit that determines how we process internal and external stimuli.
The Decline of American Peyote
The small, bulbous peyote cactus is central to the religious rituals of the Native American Church, but poaching and unsustainable harvesting practices put it at risk of extinction in the United States.
Researchers Gave Octopuses MDMA in the Name of Science
The human and octopus lineages split 500 million years ago, but apparently we both retained the gene for partying.
Why Does DMT Make You Feel Like You’re Dying?
Researchers dosed 13 people with DMT to investigate the similarities between DMT trips and near death experiences in the first study of its kind.
LSD and DMT Caused the Brain to Form New Connections in Flies and Rats
The effects of psychedelic drugs on neurite density is a promising sign that they may be useful in treating depression, anxiety and post-traumatic stress disorder.
Scientists Want the FDA to Designate MDMA a 'Breakthrough Therapy' for PTSD
A new study found ecstasy and psychotherapy “significantly decreased” symptoms of PTSD in veterans and first responders.
Stop Policing Psychedelic Science
Researchers make the case for a new, psychedelics-only controlled substance category.
America's Trippiest Chemist: Making Psychedelics 'Was Fun'
For over 40 years, Dave Nichols had government license to make Schedule 1 drugs like LSD and DMT for research.
Taking Acid for the First Time? Read This Vintage Guide
Pro tips from a no-nonsense 1967 manual on what to expect when the stuff kicks in.
The Long, Hard Road to a Science of Bad Drug Trips
If we’re going to use psychedelics for therapy, we’re going to have to figure out the proverbial bad trip.
When the Drugs Hit
A Motherboard journey into the science, politics, and culture of today’s psychedelic renaissance.